منابع مشابه
Helminths and Immunological Tolerance
Current immunosuppression regimens for solid-organ transplantation have shown disappointing efficacy in the prevention of chronic allograft rejection and carry unacceptable risks including toxicity, neoplasia, and life-threatening infection. Achievement of immunological tolerance (long-term antigen unresponsiveness in an immunocompetent host) presents the exciting prospect of freedom from immun...
متن کاملHelminths and Immunological Tolerance: Erratum
issue of Transplantation, was published under the wrong creative commons license. The article should have been published under the CC-BY license that is stated here: This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
متن کاملParasitic Helminths: New Weapons against Immunological Disorders
The prevalence of allergic and autoimmune diseases is increasing in developed countries, possibly due to reduced exposure to microorganisms in childhood (hygiene hypothesis). Epidemiological and experimental evidence in support of this hypothesis is accumulating. In this context, parasitic helminths are now important candidates for antiallergic/anti-inflammatory agents. Here we summarize antial...
متن کاملImmunological Tolerance and Enhancement
This book is part of a series called Fundamental and Clinical Aspects of Internal Medicine, a series of volumes for a postgraduate course. Short chapters cover the subjects of cytogenetics, mendelian genetics, genetic markers, multifactorial inheritance, biochemical genetics, genetics of cancer, and treatment of genetic disease. It attempts to be a fairly comprehensive resource for clinicians w...
متن کاملImmunological Tolerance
Grand ChallenGes The question of self–non-self discrimination, and thereby immunological tolerance, is as old as our appreciation of the receptor-diversity in the immune system. Initially negative selection of self-reactive lymphocytes by clonal deletion in primary lymphoid organs, enhanced by promiscuous expression of ectopic antigens in these organs, attracted attention. It became clear, howe...
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ژورنال
عنوان ژورنال: Transplantation
سال: 2014
ISSN: 0041-1337
DOI: 10.1097/tp.0b013e3182a53f59